Primary (Essential) Hypertension vs secondary hypertension

Hypertension: Definition, Symptoms and treatment

High blood pressure refers to a chronic medical condition in which the force of blood against the walls of the arteries is consistently too high. Blood pressure is measured in millimeters of mercury (mmHg) and is represented by two numbers: systolic pressure over diastolic pressure.

Hypertension, also known as high blood pressure, is a chronic medical condition that affects millions of people worldwide. It occurs when the force of blood against the walls of the arteries is consistently too high, putting strain on the cardiovascular system.

When blood pressure is consistently high, it puts strain on the arteries and organs, leading to several complications:

Hypertension can contribute to the development of heart disease, including coronary artery disease, heart failure, and abnormal heart rhythms. It can also lead to the thickening and narrowing of blood vessels, increasing the risk of heart attacks and strokes.

Uncontrolled high blood pressure can damage the blood vessels in the kidneys, affecting their ability to filter waste and fluid properly.

Prolonged high blood pressure can increase the risk of stroke, transient ischemic attacks (mini-strokes), and cognitive decline.

The prevalence of  high blood pressure varies across different regions. In the United States, the Centers for Disease Control and Prevention (CDC) estimates that around 45% of adults have hypertension.

 In Europe, the prevalence rates differ among countries, with some having higher rates than others. For example, according to the “European Society of Cardiology”, the prevalence of hypertension in Western Europe ranges from approximately 30% to 60% in adults.

Symptoms of hypertension are often not immediately apparent, which is why it is sometimes referred to as the “silent killer.” However, some individuals may experience symptoms such as: Headaches, Shortness of breath, Dizziness, Chest pain, Vision problems.

Treatment for hypertension typically involves a combination of lifestyle modifications and, in some cases, medication. Common treatment approaches include:

1.   Lifestyle modifications

This includes adopting a healthy diet, such as the Dietary Approaches to Stop Hypertension (DASH) diet, engaging in regular physical activity and maintaining a healthy weight.

Numerous studies, including randomised controlled trials and meta-analyses, have demonstrated the effectiveness of lifestyle modifications in lowering blood pressure and reducing the risk of cardiovascular events.

2.  Medication

a.   Diuretics

Diuretics, such as thiazide diuretics, help eliminate excess sodium and water from the body, reducing blood volume and lowering blood pressure. Diuretics have been extensively studied in large clinical trials and have consistently shown to effectively lower blood pressure and reduce cardiovascular events.

b.   Angiotensin-Converting Enzyme (ACE) inhibitors and Angiotensin II Receptor Blockers (ARBs)

These medications block the effects of angiotensin, a hormone that constricts blood vessels, thereby relaxing and widening the blood vessels.

ACE inhibitors and ARBs are supported by numerous randomised controlled trials, demonstrating their efficacy in lowering blood pressure and reducing the risk of cardiovascular events.

when high blood pressure occurs?

High blood pressure can occur due to a combination of various factors. Here are some of the common causes and risk factors associated with hypertension:

Primary (Essential) Hypertension

Primary hypertension refers to high blood pressure without a specific underlying cause. It is the most common form of hypertension, accounting for the majority of cases.

  • Secondary Hypertension: Secondary hypertension refers to high blood pressure caused by an underlying health condition. It accounts for a smaller proportion of hypertension cases.
  • Lifestyle Factors: Unhealthy lifestyle choices can contribute to the development of hypertension. These include a diet high in sodium and saturated fats, low intake of fruits and vegetables, and chronic stress.
  • Age: The risk of developing hypertension increases with age. As individuals get older, the blood vessels become less elastic, and the blood pressure tends to rise.
  • Family History: Having a family history of hypertension increases the likelihood of developing high blood pressure. Genetic factors may play a role in the development of hypertension.
  • Obesity and Overweight: Excess weight, particularly abdominal obesity, is strongly associated with hypertension. Adipose tissue produces hormones and substances that can contribute to increased blood pressure.
  • Ethnicity: Certain ethnic groups, such as African Americans, have a higher prevalence of  high blood pressure compared to other populations. They are also at a higher risk of developing complications related to hypertension.
  • Other factors that can contribute to the development of  high blood pressure include chronic kidney disease, diabetes, high cholesterol levels, certain medications (such as corticosteroids), and certain chronic conditions (such as autoimmune disorders).

What is secondary hypertension?

Secondary hypertension refers to high blood pressure that is caused by an underlying medical condition or as a result of certain medications.

Other types of hypertension

  • Isolated Systolic Hypertension: This type of hypertension occurs when only the systolic blood pressure (the top number in a blood pressure reading) is consistently elevated, while the diastolic blood pressure (the bottom number) remains within the normal range
  • Malignant Hypertension: Malignant hypertension is an extremely severe form of high blood pressure characterised by a rapid and significant increase in blood pressure. It can cause damage to organs such as the brain, heart, kidneys, and eyes and requires immediate medical attention.

The difference between secondary hypertension and the normal hypertension

a.   secondary hypertension

secondary hypertension is directly linked to an underlying condition or medication use and it can often be managed effectively or even resolved

b.   normal hypertension

Primary hypertension typically has no identifiable cause and develops gradually over time and it may require ongoing management and lifestyle modifications to control blood pressure levels.

What are the symptoms of  hypertension?

Hypertension is often referred to as a “silent killer” because it typically does not cause noticeable symptoms in its early stages. Many people with hypertension may not be aware of their condition. However, in some cases, hypertension can present with certain symptoms. These may include

  • 1.   Headaches: Some individuals with high blood pressure may experience frequent headaches, particularly in the back of the head. However, headaches are a nonspecific symptom and can have various causes.
  • 2.    Dizziness or lightheadedness:  Feeling dizzy or lightheaded can occasionally be associated with high blood pressure, especially during sudden changes in body position. However, there are numerous other potential causes for these symptoms as well.
  • 3.    Shortness of breathSevere  high blood pressure can lead to fluid buildup in the lungs, resulting in difficulty breathing or shortness of breath. This symptom is more commonly associated with hypertensive emergencies.
  • 4.    Chest pain: In rare cases, extremely high blood pressure can cause chest pain. However, chest pain is more commonly linked to other heart or cardiovascular conditions.

How to understand high blood pressure readings

A high blood pressure reading indicates that the force of blood against the walls of the arteries is consistently higher than normal. Blood pressure readings consist of two numbers: systolic pressure over diastolic pressure.

Systolic pressure represents the force exerted on the artery walls when the heart contracts, while diastolic pressure represents the force when the heart is at rest between beats. The unit of measurement for blood pressure is millimetres of mercury (mmHg).

How to understand high blood pressure readings

·      Normal Blood Pressure

 A normal blood pressure reading is typically considered to be around 120/80 mmHg.

·      Elevated Blood Pressure

 An elevated blood pressure reading falls between 120-129 mmHg systolic and less than 80 mmHg diastolic.

·      Hypertension Stage 1

Hypertension stage 1 is defined as a systolic pressure ranging from 130-139 mmHg or a diastolic pressure ranging from 80-89 mmHg.

·      Hypertension Stage 2

 Hypertension stage 2 is characterised by a systolic pressure of 140 mmHg or higher or a diastolic pressure of 90 mmHg or higher.

·      Hypertensive Crisis

A hypertensive crisis occurs when blood pressure readings reach 180/120 mmHg or higher.

Table that summarising the blood pressure ranges

CategorySystolic Pressure (mmHg)Diastolic Pressure (mmHg)
NormalBelow 120Below 80
Elevated120-129Less than 80
Hypertension Stage 1130-13980-89
Hypertension Stage 2140 or higher90 or higher
Hypertensive Crisis180 or higher120 or higher
Table that summarising the blood pressure ranges

Is there a correlation between high blood pressure and nosebleeds?

Yes, there can be a correlation between high blood pressure and nosebleeds, although it is not a direct cause-and-effect relationship. Let me explain further:

Nosebleeds, also known as epistaxis, can occur due to various factors, including dry air, nasal irritation, trauma, allergies, and certain medical conditions.

While high blood pressure itself does not directly cause nosebleeds, uncontrolled or severely high blood pressure can potentially contribute to their occurrence or make them more frequent.

What are the hypertension risks for the pregnant?

Normal blood pressure for the pregnant

A normal blood pressure reading during pregnancy is typically below 120/80 mmHg. The systolic pressure should be below 120 mmHg, and the diastolic pressure should be below 80 mmHg.

Risks of Hypertension During Pregnancy

Hypertension during pregnancy, including gestational hypertension and preeclampsia, can pose risks to both the mother and the baby. Some potential risks include:

1.   Reduced Blood Flow to the Placenta

High blood pressure can affect the blood vessels supplying the placenta, leading to reduced blood flow. This can impair the delivery of oxygen and nutrients to the growing foetus, potentially affecting its growth and development.

2.   Preterm Birth

Hypertension during pregnancy increases the risk of preterm birth (delivery before 37 weeks of gestation), which can result in complications for the baby.

3.   Placental Abruption

Hypertension increases the risk of placental abruption, a condition where the placenta separates from the uterine wall before delivery. This can cause bleeding, foetal distress, and potentially life-threatening complications for both the mother and the baby.

What is the correlation between smoking and hypertension?

Smoking causes an immediate increase in blood pressure. The chemicals in tobacco smoke, such as nicotine, lead to the constriction of blood vessels, resulting in elevated blood pressure levels. This effect can be observed both in occasional and regular smokers. The correlation between smoking and hypertension is well-documented in scientific research.

A study published in “the American Journal of Hypertension” in 2012 examined the relationship between smoking and blood pressure. The researchers found that both current and former smokers had higher blood pressure. 

Smoking over an extended period is associated with a higher risk of developing chronic high blood pressure. Chronic hypertension refers to consistently elevated blood pressure levels over time. 

A meta-analysis published in the Journal of  high blood pressure in 2014 analysed data from 67 studies on the association between smoking and hypertension, with current smokers having a higher risk of developing hypertension compared to non-smokers.

 Quitting smoking can lead to a decrease in blood pressure over time. The harmful effects of smoking on blood vessels can be reversed, and blood pressure levels can return to normal or decrease.

A study published in “the Journal of the American Heart Association” in 2017 found that smokers who quit experienced a gradual reduction in blood pressure over several years.

How hypertension being diagnosed?

Hypertension is diagnosed through a systematic approach that involves scientific methods and guidelines. The diagnosis of hypertension is essential due to its association with various cardiovascular diseases.

1.   Blood Pressure Measurement

The primary method for diagnosing hypertension is measuring blood pressure. Blood pressure is the force exerted by the blood against the walls of the arteries as the heart pumps it around the body.

2.   Diagnostic Criteria

 Diagnostic criteria for  high blood pressure are established by authoritative organisations such as the American Heart Association (AHA), the European Society of Cardiology (ESC), and others. The current guidelines define hypertension as a persistent elevation of blood pressure equal to or above 130/80 mmHg.

3.   Accurate Measurement

 Accurate measurement of blood pressure is crucial for an accurate diagnosis. Blood pressure measurements should be taken using calibrated instruments, such as a sphygmomanometer.

Importance of Diagnosing Hypertension

Early Detection

 Diagnosing hypertension is crucial because it allows for early detection and intervention. High blood pressure often develops silently without noticeable symptoms.

Risk Assessment

 Diagnosing hypertension helps assess a person’s overall cardiovascular risk. Hypertension is a significant risk factor for conditions such as heart disease, stroke, kidney disease, and peripheral artery disease.

Treatment and Management

 Diagnosing hypertension enables the initiation of appropriate treatment and management strategies. Lifestyle modifications, such as adopting a healthy diet, regular physical activity, and smoking cessation, are commonly recommended for individuals with hypertension.

What are the treatment options for hypertension?

There are several treatment options available for hypertension (high blood pressure). The choice of treatment depends on the severity of hypertension, the presence of other medical conditions, and individual factors. Here are the different treatment options for high blood pressure. 

  • Dietary Approaches: Adopting a healthy eating plan, such as the DASH (Dietary Approaches to Stop high blood pressure) diet, which emphasises fruits, vegetables, whole grains, lean proteins, and low-fat dairy products. Reducing sodium (salt) intake is also recommended.
  • Weight Management: Losing excess weight through a combination of healthy eating and regular physical activity.
  • Regular Exercise: Engaging in aerobic exercise, such as brisk walking, jogging, swimming, or cycling, for at least 150 minutes per week.
  • Limiting Alcohol Consumption: Moderate alcohol intake is recommended, which means up to one drink per day for women and up to two drinks per day for men.
  • Smoking Cessation: Quitting smoking is strongly advised as smoking contributes to elevated blood pressure and cardiovascular disease.
  • Diuretics: Diuretics help eliminate excess fluid and sodium from the body, reducing blood volume and lowering blood pressure. Examples include thiazide diuretics like hydrochlorothiazide.
  • Angiotensin-Converting Enzyme (ACE) Inhibitors: ACE inhibitors block the production of a hormone called angiotensin II, which causes blood vessels to narrow. This results in blood vessel relaxation and lowered blood pressure. Examples include lisinopril, enalapril.
  • Angiotensin II Receptor Blockers (ARBs): ARBs block the action of angiotensin II, leading to blood vessel relaxation and decreased blood pressure. Examples include losartan, valsartan.
  • Calcium Channel Blockers (CCBs): CCBs prevent calcium from entering the muscle cells of the heart and blood vessels, causing blood vessels to relax and blood pressure to decrease. Examples include amlodipine, diltiazem.
  • Beta-Blockers: Beta-blockers reduce the heart rate and the force of contraction, reducing the workload on the heart and lowering blood pressure. Examples include metoprolol, propranolol.
  • Complementary and Alternative Therapies: Some individuals may choose to explore complementary and alternative therapies to help manage blood pressure. These may include relaxation techniques, such as deep breathing exercises, meditation, or yoga.
what are the home remedies for hypertension

While lifestyle modifications and medical treatments are the primary approaches for managing hypertension (high blood pressure), there are also several home remedies that can complement these efforts.

  • Reduce Sodium Intake: Limiting sodium (salt) consumption can help lower blood pressure. Avoid processed and packaged foods that are high in sodium and opt for fresh, whole foods instead.
  • Increase Potassium Intake: Consuming potassium-rich foods can help counteract the effects of sodium and lower blood pressure. Good sources of potassium include bananas, oranges, avocados, leafy greens, and potatoes.
  • Adopt the DASH Diet: The Dietary Approaches to Stop high blood pressure (DASH) diet emphasises fruits, vegetables, whole grains, lean proteins, and low-fat dairy products. It has been shown to be effective in reducing blood pressure.
  • ·  Engage in Aerobic Exercise: Regular aerobic exercise, such as brisk walking, jogging, swimming, or cycling, can help lower blood pressure. Aim for at least 150 minutes of moderate-intensity aerobic activity or 75 minutes of vigorous-intensity aerobic activity per week.
  • Practice Relaxation Techniques: Chronic stress can contribute to high blood pressure. Engage in relaxation techniques such as deep breathing exercises, meditation, yoga, or tai chi to help manage stress levels.
  • Herbal Remedies: Some herbal remedies have been traditionally used to manage blood pressure, but their effectiveness and safety may vary. Examples include garlic, hawthorn, green tea extract, and basil.

how to protect yourself from high blood pressure?

Protecting yourself from high blood pressure is very important, as uncontrolled high blood pressure can lead to serious health

Ways to Protect Yourself from hypertension

  • Identify stressors: Recognize the factors that contribute to your stress. It could be work-related pressures, relationship issues, financial concerns, or other life challenges.
  • Practice relaxation techniques: Engage in relaxation techniques such as deep breathing exercises, meditation, yoga, or progressive muscle relaxation.
  • Exercise regularly: Physical activity is an excellent stress reliever. Regular exercise releases endorphins, which are natural mood boosters. Aim for at least 30 minutes.

 In Conclusion, High blood pressure is a prevalent condition that requires proactive management to minimise the risk of complications. By adopting a healthy lifestyle, including a balanced diet, regular exercise ,individuals can significantly lower their blood pressure levels and improve their overall well-being.